Facial mask products establish mild antiseptic system ingredients recommended

Facial mask products establish mild antiseptic system ingredients recommended

Summary

Facial mask products include three main materials: sheet mask fabric, cosmetic body and packaging bag. Considering the various instabilities produced during processing and storage, it is necessary to add a preservative system that combines and adapt to the cosmetic body to improve the overall stability of the product, reduce the sensitization rate, and provide cosmetic effects.

Facial mask products establish mild antiseptic system ingredients recommended
Facial mask products include three main materials: sheet mask fabric, cosmetic body and packaging bag. Considering the various instabilities produced during processing and storage, it is necessary to add a preservative system that combines and adapt to the cosmetic body to improve the overall stability of the product, reduce the sensitization rate, and provide cosmetic effects.
We need to first have a preliminary understanding of the mechanism of skin sensitization:
1.The mechanism of skin itching
✔Histamine receptors (H1/H4): Degranulation of mast cells releases histamine, which binds to the C-terminal H1 receptor.
Protease Activated Receptor-2 (PAR-2): Activates the C-terminus of PAR-2, induces the release of calcitonin gene-related peptide (CGRP) and substance P, and transmits itch signals to the brain.
Neurokinin receptor (NK-1): Substance P induces histamine release by binding to neurokinin receptor (NK-1) located in mast cells.

2.Mechanism of skin tingling/burning sensation
   The peripheral nervous system in the skin innervates
Sensory receptors are expressed on various nerve fibers and keratinocytes
These receptors regulate the body's perception of pain, heat, burning, itching and tingling
TRPV1 (transient receptor potential vanilloid subtype 1 channel protein) is present in unmyelinated C-fibers and AS fibers and mainly regulates the body's perception of burning, pain, and tingling.
After understanding the mechanism of skin sensitization, we recommend using relatively mild preservative system ingredients to add.

SymSave@H
Multifunctional cosmetic raw materials
Natural equivalent
INCI: p-Hydroxyacetophenone

Hydrolite@5
Excellent moisturizer with additional broad-spectrum antibacterial power
Long history of safe use Multifunctional features 
INCI: 1,2-Pentanediol

Hydrolite@6O
Multifunctional 1,2-alkanediol with moisturizing and broad-spectrum antibacterial properties
High purity, low odor
INCI: 1,2-Hexanediol

SymDiol@68
Formulated with moisturizing 1,2-alkyl alcohols
Excellent broad-spectrum antimicrobial activity
INCI: 1,2-Hexanediol (and) Caprylyl Glycol

SymDiol@68T
1,2-Alkyl alcohol complexed with cycloheptatrienol ketone
Multifunctional antioxidant, moisturizing, antibacterial ingredients
INCI: 1,2-hexanediol, caprylyl glycol, cycloheptatrienolone

SymTriol@MBA
1,2-Alkyl alcohol complexed with cycloheptatrienol ketone
Multifunctional antioxidant, moisturizing, antibacterial ingredients
INCI: 1,2-hexanediol, caprylyl glycol, cycloheptatrienolone

After the preservative system is formed, the antibacterial ability needs to be tested by the European Pharmacopoeia method. The test sample adopts the following 4 different microorganisms:
•Gram-negative bacteria -Pseudomonas aeruginosa(ATCC 9027)
Gram-positive bacteria - Staphylococcus aureus(ATCC6538) 
Yeast -Candida albicans(ATCC10231) 
Fungi -Aspergillus niger(ATCC16404)

Samples stored at a specific temperature and taken out for counting at specific intervals (0, 2, 7, 14 and 28 days)
The number of microorganisms in the test sample was detected by plate colony counting method to measure and count the antiseptic effect.



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